Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004278)
Formula Reactant Misonidazole Product Nitroso
Reactant Info Product Info
Metabolic Type Reduction - Reduction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004284 Misonidazole Desmethylmisonidazole Unclear Misonidazole [1]
MR004281 Misonidazole [1-(2-aminoimidazol-1-yl)-3-methoxypropan-2-ol] (AIM) Unclear Misonidazole [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004279 Nitroso N-hydroxylamine Reduction - Reduction Misonidazole [3]
References
1 Kinetic aspects of misonidazole and its major metabolite in radiotherapy
2 Comparative misonidazole metabolism in anaerobic bacteria and hypoxic Chinese hamster lung fibroblast (V-79-473) cells
3 Reductive metabolism and DNA binding of misonidazole

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