Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004377)
Formula
SVG example
Reactant Nitrophenyl acetate Product Acetaldehyde
Reactant Info Product Info
Metabolic Enzyme Aldehyde dehydrogenase 1 (ALDH1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004376 Nitrophenyl acetate Nitrophenyl acetate Metabolite B1 Oxidation - Hydrolyzationn Nitrophenyl acetate [1]
MR004378 Nitrophenyl acetate Nitrophenyl acetate Metabolite B2 Unclear Nitrophenyl acetate [2]
MR004379 Nitrophenyl acetate Nitrophenyl acetate Metabolite B3 Unclear Nitrophenyl acetate [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000453 BRN-1736748 Acetaldehyde Unclear BRN-1736748 [4], [5]
MR008004 Cefuroxime axetil Acetaldehyde Unclear - Unclear Cefuroxime axetil [6]
MR007449 Ethanol Acetaldehyde Oxidation - Oxidationn Ethanol [7]
MR005911 2-deoxy-D-ribose 5-phosphate (DR5P) Acetaldehyde Unclear Thymidine [8]
MR004209 PYR Acetaldehyde Unclear D-xylulose [9]
MR004160 4-Hydroxy-2-oxovaleric acid Acetaldehyde Unclear Aminophenol [10]
⏷ Show the Full List of MR
References
1 Hydrolysis of 4-nitrophenyl acetate catalyzed by carbonic anhydrase III from bovine skeletal muscle. J Biol Chem. 1986 Aug 5;261(22):10100-3.
2 From a metagenomic source to a high-resolution structure of a novel alkaline esterase
3 Characterisation of a Novel Acetyl Xylan Esterase (BaAXE) Screened from the Gut Microbiota of the Common Black Slug (Arion ater)
4 Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease Nature. 2011 Apr 7;472(7341):57-63. doi: 10.1038/nature09922.
5 NORMAN Suspect List Exchange:Choline
6 DrugBank(Pharmacology-Metabolism):Cefuroxime axetil
7 Ethanol Metabolism in the Liver, the Induction of Oxidant Stress, and the Antioxidant Defense System
8 Thymidine catabolism as a metabolic strategy for cancer survival. Cell Rep. 2017 May 16;19(7):1313-1321.
9 Effects of increased transaldolase activity on D-xylulose and D-glucose metabolism in Saccharomyces cerevisiae cell extracts
10 Metabolism of 2-aminophenol by Pseudomonas sp. AP-3: modified meta-cleavage pathway

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