Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004458)
Formula
PTE
SVG example
Hydrolyzationn
Reactant Paraoxon Product p-nitrophenol
Reactant Info Product Info
Metabolic Enzyme phosphotriesterase (PTE) DME Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004457 Paraoxon Diethylphosphoric acid Oxidation - Hydrolyzationn Paraoxon [1]
MR004459 Paraoxon Paraoxon Metabolite C3 Unclear Paraoxon [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004380 Nitrophenylphosphate p-nitrophenol Oxidation - Hydrolyzationn Nitrophenylphosphate [3]
References
1 Encapsulation of phosphotriesterase within murine erythrocytes
2 Paraoxon hydrolysis vs. covalent binding in the elimination of paraoxon in the rabbit
3 Paraoxon, 4-nitrophenyl phosphate and acetate are substrates of - but not of -, - and -carbonic anhydrases. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6208-12.

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