Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004468)
Formula Reactant 9,10-Phenanthrene hydroquinone Product O-mono-methyl catechol
Reactant Info Product Info
Metabolic Enzyme Catechol O-methyltransferase (COMT) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004465 Phenanthrenequinone 9,10-Phenanthrene hydroquinone Reduction - Reduction Phenanthrenequinone [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004467 9,10-Phenanthrene hydroquinone O-mono-glucuronosyl catechol Unclear Phenanthrenequinone [1]
MR004469 9,10-Phenanthrene hydroquinone O-mono-methyl-O-mono-sulfonated catechol Unclear Phenanthrenequinone [1]
MR004466 9,10-Phenanthrene hydroquinone O-mono-sulfonated catechol Unclear Phenanthrenequinone [1]
References
1 Metabolism of a representative oxygenated polycyclic aromatic hydrocarbon (PAH) phenanthrene-9,10-quinone in human hepatoma (HepG2) cells
2 Cytotoxicity of Air Pollutant 9,10-Phenanthrenequinone: Role of Reactive Oxygen Species and Redox Signaling

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