Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004499)
Formula
SVG example
Reactant 3-(3'-Hydroxyphenyl)propionic acid Product 3'-Hydroxyphenylacetic acid
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006953 AS-63093 3-(3-Hydroxyphenyl)propanoic acid Unclear AS-63093 [1]
MR009195 3-(Dihydroxyphenyl)propanoic acid 3-(3'-Hydroxyphenyl)propanoic acid Oxidation - Dehydroxylation 3,4-Dihydroxycinnamic Acid [2]
MR004496 3-(3',4'-Dihydroxyphenyl)propionic acid 3-(3'-Hydroxyphenyl)propionic acid Reduction - Dehydroxylation VS-12343 [3]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009196 3-(3'-Hydroxyphenyl)propanoic acid 3-(phenyl)propanoic acid Oxidation - Dehydroxylation 3,4-Dihydroxycinnamic Acid [2]
MR004497 3-(3'-Hydroxyphenyl)propionic acid 3-(phenyl)propionic acid Reduction - Dehydroxylation VS-12343 [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008916 3,4-dihydroxyphenylacetic acid 3-hydroxyphenylacetic acid Unclear - Unclear Docarpamine [4]
MR004489 3'-4'-Dihydroxyphenylacetic acid 3'-Hydroxyphenylacetic acid Unclear VS-12343 [3]
MR013973 3',4'-dihydroxyphenylacetic acid 3'-hydroxyphenylacetic acid Unclear Epigallocatechin gallate [5]
MR013566 3',4'-dihydroxyphenylacetic acid 3'-hydroxyphenylacetic acid Unclear Epigallocatechin gallate [5]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004492 3'-Hydroxyphenylacetic acid 3-Hydroxybenzoic acid Unclear VS-12343 [3]
MR004490 3'-Hydroxyphenylacetic acid Phenylacetic acid Unclear VS-12343 [3]
References
1 Studies on pharmacokinetic drug interaction potential of vinpocetine. Medicines (Basel). 2015 Jun 5;2(2):93-105.
2 In vitro catabolism of 3',4'-dihydroxycinnamic acid by human colonic microbiota
3 Biotransformation of two citrus flavanones by lactic acid bacteria in chemical defined medium
4 Metabolism of a new orally active dopamine prodrug, N-(N-acetyl-L-methionyl)-O,O-bis(ethoxycarbonyl)dopamine (TA-870) and dopamine after oral administration to rats and dogs
5 Absorption, metabolism, bioactivity, and biotransformation of epigallocatechin gallate

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