Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004610)
Formula Reactant Befunolol Product 2-acetyl-4-hydroxy-7-(2- hydroxy-3-isopropylaminopropoxy)benzofuran
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004615 Befunolol 2-(1-hydroxyethyl)-7-(2-hydroxy-3-isopropylaminopropoxy)benzofuran Unclear Befunolol [1]
MR004613 Befunolol Befunolol Metabolite Unclear Befunolol [2]
MR004623 Befunolol Befunolol Metabolite BF-7-OG Unclear Befunolol [2]
MR004622 Befunolol Dihydrobefunolol Reduction - Reduction Befunolol [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004611 2-acetyl-4-hydroxy-7-(2- hydroxy-3-isopropylaminopropoxy)benzofuran Befunolol Metabolite Unclear Befunolol [2]
MR004617 2-acetyl-4-hydroxy-7-(2- hydroxy-3-isopropylaminopropoxy)benzofuran Befunolol Metabolite M2G Unclear Befunolol [1]
References
1 Enzyme immunoassays for beta-adrenoreceptor blocking agent, befunolol and its main metabolite, M1
2 [Identification of urinary metabolites of befunolol in dog and man principally by mass spectrometry (author's transl)]
3 Purification and characterization of befunolol reductase from rabbit liver

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