Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004651)
Formula
SVG example
Reactant 4-Hydroxyifosfamide Product Aldoifosfamide
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004650 Ifosfamide 4-Hydroxyifosfamide Oxidation - 4-hydroxylation Ifosfamide [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004658 4-Hydroxyifosfamide 4-Ketoifosfamide Unclear Ifosfamide [1]
MR004659 4-Hydroxyifosfamide 4-Thioifosfamide Conjugation - Glutathione conjugation Ifosfamide [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004654 Aldoifosfamide Acrolein Unclear Ifosfamide [1]
MR004657 Aldoifosfamide Alcoifosfamide Unclear Ifosfamide [2]
MR004656 Aldoifosfamide Carboxylifosfamide Unclear Ifosfamide [2]
MR004652 Aldoifosfamide Isophosphamide mustard Unclear Ifosfamide [3]
References
1 The KEGG resource for deciphering the genome
2 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
3 DrugBank(Pharmacology-Metabolism):Ifosfamide

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.