Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004690)
Formula
SVG example
11-oxidation
Reactant Methylprednisolone M13 Metabolite Product Methylprednisolone M15 Metabolite
Reactant Info Product Info
Metabolic Enzyme Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1) DME Info
Metabolic Type Oxidation - 11-oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004689 Methylprednisolone Methylprednisolone M13 Metabolite Oxidation - 22-hydroxylation Methylprednisolone [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004691 Methylprednisolone M13 Metabolite Methylprednisolone M14 Metabolite Reduction - 20-reduction Methylprednisolone [1], [2]
References
1 Urinary profile of methylprednisolone and its metabolites after oral and topical administrations
2 Carbonyl reduction pathways in drug metabolism

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