Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004990)
Formula Reactant Ticlopidine Product Dehydrogenated ticlopidine
Reactant Info Product Info
Metabolic Enzyme Myeloperoxidase (MPO) DME Info
Metabolic Type Oxidation - Dehydrogenation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004989 Ticlopidine 2-Chloroticlopidine Unclear Ticlopidine [1]
MR004982 Ticlopidine 2-Oxoticlopidine Unclear Ticlopidine [1]
MR004993 Ticlopidine 7-Hydroxyticlopidine Unclear Ticlopidine [2]
MR004992 Ticlopidine Di-Hydroxyticlopidine Unclear Ticlopidine [1]
MR004984 Ticlopidine Thienodihydropyridinium Oxidation - Dehydrogenation Ticlopidine [1]
MR004991 Ticlopidine Ticlopidine N-oxide Oxidation - N-oxidation Ticlopidine [1]
MR004987 Ticlopidine Ticlopidine S-oxide Unclear Ticlopidine [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
2 DrugBank(Pharmacology-Metabolism):Ticlopidine

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