Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005169)
Formula
SVG example
Reactant Pirprofen Product Epoxide metabolite
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005176 Pirprofen Amino-metabolite Unclear Pirprofen [1]
MR005172 Pirprofen Pirprofen glucuronide Conjugation - Glucuronidation Pirprofen [1], [2]
MR005174 Pirprofen Pyrrole M1 Unclear Pirprofen [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005170 Epoxide metabolite Trans-diol metabolite Oxidation - Hydrolyzationn Pirprofen [1]
MR005178 Epoxide metabolite Unclear Conjugation - Glucuronidation Pirprofen [1]
References
1 High-performance liquid chromatographic determination of pirprofen and five of its metabolites in human plasma without hydrolysis and in human urine before and after chemical hydrolysis
2 Glucuronidation of 2-arylpropionic acids pirprofen, flurbiprofen, and ibuprofen by liver microsomes. Drug Metab Dispos. 1990 Sep-Oct;18(5):692-7.

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