Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005318)
Formula
CYP1A2 ...
SVG example
Oxidationn
Reactant Cyamemazine Product Cyamemazine sulfoxide
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005317 Cyamemazine N-desmethyl cyamemazine Oxidation - N-demethylation Cyamemazine [1], [2]
References
1 Active cyamemazine metabolites in patients treated with cyamemazine (Tercian?): influence on cerebral dopamine D2 and serotonin 5-HT (2A) receptor occupancy as measured by positron emission tomography (PET)
2 Characterization of human cytochrome P450 enzymes involved in the metabolism of cyamemazine. Eur J Pharm Sci. 2007 Dec;32(4-5):357-66.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.