Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005329)
Formula
SVG example
Reduction
Reactant Dehydrocholic acid Product Dihydroxymonoketo bile acid
Reactant Info Product Info
Metabolic Enzyme Beta-hydroxysteroid dehydrogenase (hdhB) DME Info
Metabolic Type Reduction - Reduction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005331 Dehydrocholic acid Cholic acid Reduction - Reduction Dehydrocholic acid [1], [2]
MR005330 Dehydrocholic acid Monohydroxydiketoacid Reduction - Reduction Dehydrocholic acid [1], [2]
References
1 Triketocholanoic (dehydrocholic) acid. Hepatic metabolism and effect on bile flow and biliary lipid secretion in man
2 Identification, cloning, heterologous expression, and characterization of a NADPH-dependent 7beta-hydroxysteroid dehydrogenase from Collinsella aerofaciens. Appl Microbiol Biotechnol. 2011 Apr;90(1):127-35.

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