Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005369)
Formula
SVG example
Oxidationn
Reactant 12-Hydroxydodecanoic Acid Product 12,12-Dihydroxydodecanoic Acid
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 4A10 (Cyp4a1) DME Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005368 Lauric acid 12-Hydroxydodecanoic Acid Oxidation - Aliphatic hydroxylation Lauric acid [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005370 12,12-Dihydroxydodecanoic Acid Dodecanedioic Acid Oxidation - Oxidationn Lauric acid [1], [2]
References
1 The omega-hydroxlyation of lauric acid: oxidation of 12-hydroxlauric acid to dodecanedioic acid by a purified recombinant fusion protein containing P450 4A1 and NADPH-P450 reductase
2 Cytochrome P450 4A11 inhibition assays based on characterization of lauric acid metabolites

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.