Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005430)
Formula Reactant Avapritinib Product M499
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A3 (UGT1A3) DME Info
Metabolic Type Oxidation - Oxidationn deamination
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005429 Avapritinib M690 Conjugation - Hydroxy glucuronidation Avapritinib [1]
MR005428 Avapritinib Unclear Unclear Avapritinib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010830 Dezocine M499 Unclear - Unclear Dezocine [2]
References
1 FDA label:Avapritinib
2 Avapritinib: First Approval

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