Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005441)
Formula
SVG example
Reactant ESP15228 Product ESP15228-glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 2B7 (UGT2B7) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005432 Bempedoic acid ESP15228 Unclear Bempedoic acid [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005433 ESP15228 ESP15228-CoA Unclear Bempedoic acid [2]
MR005442 ESP15228 Hydroxymethyl-ESP 15228 Unclear Bempedoic acid [2]
References
1 Measurement of bempedoic acid and its keto metabolite in human plasma and urine using solid phase extraction and electrospray LC-MS/MS
2 The Disposition and Metabolism of Bempedoic Acid, a Potent Inhibitor of ATP Citrate Lyase, in Healthy Human Subjects

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.