Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005527)
Formula Reactant Lurbinectedin Metablite 2 Product Lurbinectedin Metablite 1
Reactant Info Product Info
Metabolic Type Oxidation - N-,O-Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005526 Lurbinectedin Lurbinectedin Metablite 2 Oxidation - O-Demethylation Lurbinectedin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005531 Lurbinectedin Lurbinectedin Metablite 1 Unclear Lurbinectedin [1]
MR005529 Lurbinectedin Metablite 6 Lurbinectedin Metablite 1 Unclear Lurbinectedin [1]
References
1 Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients

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