Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005536)
Formula Reactant Maribavir Product Maribavir M15
Reactant Info Product Info
Metabolic Type Multi-steps Reaction - Dechlorination; glutathione (GSH) conjugation; amide hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005537 Maribavir Maribavir M10 Conjugation - Glucuronidation conjugation Maribavir [1]
MR005535 Maribavir Maribavir M2 Multi-steps Reaction - Glucuronidation conjugation; deribosylation Maribavir [1]
MR005534 Maribavir Maribavir M5 Oxidation - Oxidationn Maribavir [1]
MR005532 Maribavir VP 44469 Oxidation - N-Dealkylation Maribavir [2]
References
1 Elucidation of Metabolic and Disposition Pathways for Maribavir in Nonhuman Primates through Mass Balance and Semi-Physiologically Based Modeling Approaches
2 Effect of ketoconazole on the pharmacokinetics of maribavir in healthy adults

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