Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005664)
Formula
CYP3A4 ...
SVG example
Reactant Vorapaxar sulfate metabolite M20 Product Amine metabolite M19
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2J2 (CYP2J2) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005663 Vorapaxar sulfate Vorapaxar sulfate metabolite M20 Oxidation - Hydrolyzationn Vorapaxar sulfate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005665 Vorapaxar sulfate Amine metabolite M19 Other reaction - Carbamate cleavage Vorapaxar sulfate [1]
References
1 Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 530348 (Vorapaxar), a potent oral thrombin protease-activated receptor 1 antagonist

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.