Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005694)
Formula
SVG example
Deacylation
Reactant Ziprasidone Product 6-chloro-5-(2-piperazin-1-yl-ethyl)-1,3-dihydro-indol-2-one
Reactant Info Product Info
Metabolic Type Other reaction - Deacylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005690 Ziprasidone (6-chloro-2-oxo-2,3-dihydro-1H-indol-5-yl)acetic acid Oxidation - Oxidationn N-dealkylation Ziprasidone [1]
MR005684 Ziprasidone 3-(piperazine-1-yl)-1,2-benzisothiazole Oxidation - Oxidationn N-dealkylation Ziprasidone [1]
MR005695 Ziprasidone Dihydro-ziprasidone-sulfone Multi-steps Reaction - Hydration; oxidation Ziprasidone [1]
MR005692 Ziprasidone S-Methyl-dihydro-ziprasidone Multi-steps Reaction - Methylationn; reductive cleavage Ziprasidone [1]
MR005688 Ziprasidone Ziprasidone Sulfoxide Oxidation - Oxidationn Ziprasidone [1], [2]
References
1 Metabolism and excretion of a new antipsychotic drug, ziprasidone, in humans
2 [Limits of jaw orthopedic treatment]

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