Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005771)
Formula
CYP3A4 ...
SVG example
Hydrolyzationn
Reactant Dutasteride Product 4'-hydroxydutasteride
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005773 Dutasteride 1,2-dihydrodutasteride Oxidation - Hydrolyzationn Dutasteride [1]
MR005772 Dutasteride 6beta-hydroxydutasteride Oxidation - Hydrolyzationn Dutasteride [1]
References
1 LC-MS/MS determination of dutasteride and its major metabolites in human plasma

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