Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005777)
Formula	Oxidationn
	Reactant	HO-PEG5-Naloxol	Product	Carboxymethyl-PEG4-Naloxol
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Oxidation - Oxidationn

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR005776	Naloxegol oxalate	HO-PEG5-Naloxol	Oxidation - Hydrolyzationn	Naloxegol oxalate	[1], [2]

References
1	Absorption, distribution, metabolism, and excretion of [14C]-labeled naloxegol in healthy subjects
2	Naloxegol: treatment for opioid-induced constipation in chronic non-cancer pain. Ann Pharmacother. 2015 Mar;49(3):360-5.

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