Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005779)
Formula Reactant HO-PEG4-Naloxol Product Carboxymethyl-PEG3-Naloxol
Reactant Info Product Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005778 Naloxegol oxalate HO-PEG4-Naloxol Oxidation - Hydrolyzationn Naloxegol oxalate [1], [2]
References
1 Absorption, distribution, metabolism, and excretion of [14C]-labeled naloxegol in healthy subjects
2 Naloxegol: treatment for opioid-induced constipation in chronic non-cancer pain. Ann Pharmacother. 2015 Mar;49(3):360-5.

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