| General Information of This Metabolic Reaction (MR) (ID:
MR005972) |
| Formula |
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| Reactant |
FCF-89 |
Product |
R=glucuronic acid OH or sulphate |
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Reactant Info
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Product Info
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| Other MR(s) Related to The Reactant of This MR |
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Other MR(s) That Metabolize The Reactant of This MR
|
| MR ID |
Reactant |
Product |
MR Type |
Related Drug |
REF |
|
MR005970
|
FCF-89
|
4-hydroxy-1-methyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide
|
Unclear |
FCF-89 |
[1], [2] |
|
MR005971
|
FCF-89
|
PNU-212679 N-Phenyl-N-methyl-2-oxo-4-hydroxy-1,2-dihydroquinoline-3-carboxamide
|
Unclear |
FCF-89 |
[1], [2] |
|
MR005969
|
FCF-89
|
PNU-212684 4-hydroxy-N-(4-hydroxyphenyl)-N,1-dimethyl-2-oxoquinoline-3-carboxamide
|
Unclear |
FCF-89 |
[1], [2] |
|
MR005966
|
FCF-89
|
PNU-213708 4,6-dihydroxy-N,1-dimethyl-2-oxo-N-phenylquinoline-3-carboxamide
|
Unclear |
FCF-89 |
[1], [2] |
|
MR005968
|
FCF-89
|
PNU-213831 4,8-dihydroxy-N,1-dimethyl-2-oxo-N-phenylquinoline-3-carboxamide
|
Unclear |
FCF-89 |
[1], [2] |
|
MR005967
|
FCF-89
|
PNU-214608 4,7-dihydroxy-N,1-dimethyl-2-oxo-N-phenylquinoline-3-carboxamide
|
Unclear |
FCF-89 |
[1], [2] |
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| References |
| 1 |
Absorption and disposition including enterohepatic circulation of (14C) roquinimex after oral administration to healthy volunteers
|
| 2 |
Identification of cytochrome P4503A as the major subfamily responsible for the metabolism of roquinimex in man. Xenobiotica. 2000 Sep;30(9):905-14.
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