Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006047)
Formula
SVG example
Oxidationn
Reactant Sarizotan metabolite M203 Product Sarizotan metabolite M217
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006050 EMD-128130 Sarizotan metabolite M203 Conjugation - Glycosylation EMD-128130 [1]
MR006043 EMD 329989 Sarizotan metabolite M203 Unclear EMD-128130 [2]
MR006046 Sarizotan metabolite M364A Sarizotan metabolite M203 Unclear EMD-128130 [2]
MR006049 Sarizotan metabolite M364D Sarizotan metabolite M203 Unclear EMD-128130 [2]
MR006044 Sarizotan metabolite M362 Sarizotan metabolite M203 Unclear EMD-128130 [2]
References
1 Bioactivity and metabolism of trans-resveratrol orally administered to Wistar rats
2 In vitro characterization of sarizotan metabolism: hepatic clearance, identification and characterization of metabolites, drug-metabolizing enzyme identification, and evaluation of cytochrome p450 inhibition. Drug Metab Dispos. 2010 Jun;38(6):905-16.

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