Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006123)
Formula	Hydrolyzationn; oxidation
	Reactant	N-(2-hydroxymethyl-3-chlorophenyl)-anthranilic acid	Product	N-(2-methyl-3-chloro-4-metoxyphenyl)-anthranilic acid
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Oxidation - Hydrolyzationn; oxidation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR006119	GEA-6414	N-(2-hydroxymethyl-3-chlorophenyl)-anthranilic acid	Multi-steps Reaction - Glucuronidation; hydroxylation	GEA-6414	[1]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR006120	N-(2-hydroxymethyl-3-chlorophenyl)-anthranilic acid	N-(2-carboxy-3-chlorophenyl)-anthranilic acid	Oxidation - Hydrolyzationn	GEA-6414	[1]
MR006122	N-(2-hydroxymethyl-3-chlorophenyl)-anthranilic acid	N-(2-hydroxymethyl-3-chloro-4-hydroxyphenyl)-anthranilic acid	Oxidation - Hydrolyzationn; oxidation	GEA-6414	[1]
MR006121	N-(2-hydroxymethyl-3-chlorophenyl)-anthranilic acid	N-(2-methyl-3-chloro-4-metoxyphenyl)-anthranilic	Oxidation - Hydrolyzationn; oxidation	GEA-6414	[1]

Other MR(s) Related to The Product of This MR

Other MR(s) That Produce The Product of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR006116	N-(2-methyl-3-chloro-4-hydroxyphenyl)-anthranilic acid	N-(2-methyl-3-chloro-4-metoxyphenyl)-anthranilic acid	Reduction - Dehalogenation	GEA-6414	[1]

References
1	Purification and 1H NMR spectroscopic characterization of phase II metabolites of tolfenamic acid

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