Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006125)
Formula
SVG example
Glucuronidation; hydroxylation
Reactant GEA-6414 Product N-(2-methyl-3-chlorophenyl)-5-hydroxy-anthranilic acid
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Multi-steps Reaction - Glucuronidation; hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006126 GEA-6414 Ether glucuronide ofN-(2-methyl-3-chloro-4-hydroxyphenyl)-anthranilic acid Conjugation - Glucuronidation GEA-6414 [1]
MR006124 GEA-6414 Glucuronide form of tolfenamic acid Conjugation - Glucuronidation GEA-6414 [1]
MR006119 GEA-6414 N-(2-hydroxymethyl-3-chlorophenyl)-anthranilic acid Multi-steps Reaction - Glucuronidation; hydroxylation GEA-6414 [1]
MR006114 GEA-6414 N-(2-methyl-3-chloro-4-hydroxyphenyl)-anthranilic acid Multi-steps Reaction - Glucuronidation; hydroxylation GEA-6414 [1]
MR006127 GEA-6414 N-(2-methyl-3-chloro-5-hydroxyphenyl)-anthranilic acid Conjugation - O-glucuronidation GEA-6414 [1]
MR006117 GEA-6414 N-(2-methyl-3-chloro-5-hydroxyphenyl)-anthranilic acid form 2 Multi-steps Reaction - Glucuronidation; hydroxylation GEA-6414 [1]
MR006128 GEA-6414 N-(2-methyl-3-chlorophenyl)-4-hydroxy-anthranilic acid Multi-steps Reaction - Glucuronidation; hydroxylation GEA-6414 [1]
References
1 Purification and 1H NMR spectroscopic characterization of phase II metabolites of tolfenamic acid

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.