Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006184)
Formula Reactant 3beta-OH-tibolone Product 3beta-sulfated-tibolone
Reactant Info Product Info
Metabolic Enzyme Sulfotransferase 1E1 (SULT1E1) DME Info
Sulfotransferase 2B1 (SULT2B1) DME Info
Sulfotransferase 2A1 (SULT2A1) DME Info
Metabolic Type Conjugation - Sulfation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006183 Tibolone 3beta-OH-tibolone Oxidation - Hydrolyzationn Tibolone [1], [2], [3]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006185 3beta-OH-tibolone Delta(4)-tibolone Unclear Tibolone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006186 3beta-sulfated-tibolone 3alpha-17beta-disulfated-tibolone Conjugation - Sulfation Tibolone [1], [2], [3]
References
1 Sulfation of tibolone and tibolone metabolites by expressed human cytosolic sulfotransferases. J Steroid Biochem Mol Biol. 2004 Apr;88(4-5):383-91.
2 Sulfation of tibolone metabolites by human postmenopausal liver and small intestinal sulfotransferases (SULTs). Steroids. 2006 May;71(5):343-51.
3 Antioxidant effect of the active metabolites of tibolone

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.