| General Information of This Metabolic Reaction (MR) (ID:
MR006188) |
| Formula |
Reactant |
3alpha-OH-tibolone |
Product |
3alpha-sulfated-tibolone |
|
Reactant Info
|
Product Info
|
|
Metabolic Enzyme
|
Sulfotransferase 1E1 (SULT1E1)
|
DME Info
|
|
Sulfotransferase 2B1 (SULT2B1)
|
DME Info
|
|
Sulfotransferase 2A1 (SULT2A1)
|
DME Info
|
|
Metabolic Type
|
Conjugation
-
Sulfation
|
|
|
|
|
|
|
|
| Other MR(s) Related to The Reactant of This MR |
|
Other MR(s) That Produce The Reactant of This MR
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| References |
| 1 |
Sulfation of tibolone and tibolone metabolites by expressed human cytosolic sulfotransferases. J Steroid Biochem Mol Biol. 2004 Apr;88(4-5):383-91.
|
| 2 |
Sulfation of tibolone metabolites by human postmenopausal liver and small intestinal sulfotransferases (SULTs). Steroids. 2006 May;71(5):343-51.
|
| 3 |
Antioxidant effect of the active metabolites of tibolone
|
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