Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006393)
Formula
CYP3A4 ...
SVG example
Reactant OPC-12759 Product 6-Hydroxyrebamipide
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006394 OPC-12759 8-Hydroxyrebamipide Unclear OPC-12759 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006410 PR-934423 Desglycinyl-remacemide Oxidation - Oxidationn PR-934423 [2]
References
1 Involvement of cytochrome P450 in the metabolism of rebamipide by the human liver. Xenobiotica. 2002 Jul;32(7):573-86.
2 Influence of cytochrome P450 induction on the pharmacokinetics and pharmacodynamics of remacemide hydrochloride. Epilepsy Res. 2002 May;49(3):247-54.

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