Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006443)
Formula Reactant SB-939 Metabolite M2/M3/M4 Product SB-939 Metabolite M5
Reactant Info Product Info
Metabolic Type Oxidation - N-deethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006442 SB-939 SB-939 Metabolite M2/M3/M4 Oxidation - Oxidationn SB-939 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006441 SB-939 Metabolite M1 SB-939 Metabolite M5 Oxidation - Oxidationn SB-939 [1]
References
1 Preclinical metabolism and disposition of SB939 (Pracinostat), an orally active histone deacetylase inhibitor, and prediction of human pharmacokinetics. Drug Metab Dispos. 2011 Dec;39(12):2219-32.

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