Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006507)
Formula
UGT
SVG example
Conjugation
Reactant ANW-43703 Product Salicylphenol glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronyltransferase (UGT) DME Info
Metabolic Type Conjugation - Conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006504 ANW-43703 Gentistic acid Oxidation - Aromatic hydroxylation ANW-43703 [1]
MR006506 ANW-43703 Salicylacyl glucuronide Conjugation - Conjugation ANW-43703 [1], [2]
MR006508 ANW-43703 Salicyuric acid Unclear ANW-43703 [1], [2]
References
1 Aromatic hydroxylation of salicylic acid and aspirin by human cytochromes P450. Eur J Pharm Sci. 2015 Jun 20;73:49-56.
2 Polymorphisms of Aspirin-Metabolizing Enzymes CYP2C9, NAT2 and UGT1A6 in Aspirin-Intolerant Urticaria. Allergy Asthma Immunol Res. 2011 Oct;3(4):273-6.

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