Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006521)
Formula
MAOA ...
SVG example
Oxidationn
Reactant Demethylcitalopram Product Citalopram propionaldehyde
Reactant Info Product Info
Metabolic Enzyme Monoamine oxidase type A (MAO-A) DME Info
Monoamine oxidase type B (MAO-B) DME Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006517 Citalopram hydrobromide Demethylcitalopram Oxidation - N-demethylation Citalopram hydrobromide [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006518 Demethylcitalopram Didemethylcitalopram Oxidation - N-demethylation Citalopram hydrobromide [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006522 Citalopram hydrobromide Citalopram propionaldehyde Oxidation - Oxidationn Citalopram hydrobromide [2]
MR006519 Didemethylcitalopram Citalopram propionaldehyde Oxidation - Oxidationn Citalopram hydrobromide [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006520 Citalopram propionaldehyde Citalopram propionic acid Oxidation - Oxidationn Citalopram hydrobromide [2]
References
1 PharmGKB summary: citalopram pharmacokinetics pathway. Pharmacogenet Genomics. 2011 Nov;21(11):769-72.
2 Analytical methodologies for the enantiodetermination of citalopram and its metabolites

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