Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006581)
Formula
CYP3A4 ...
SVG example
Reduction
Reactant Clonazepam Product 7-amino-clonazepam
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Metabolic Type Reduction - Reduction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006585 Clonazepam 3-hydroxy-clonazepam Oxidation - Hydrolyzationn Clonazepam [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006584 7-amino-clonazepam 3-hydroxy-7-amino-clonazepam Oxidation - Hydrolyzationn Clonazepam [1]
MR006582 7-amino-clonazepam 7-acetamido-clonazepam Conjugation - Acetylation Clonazepam [1]
References
1 Optimization of Clonazepam Therapy Adjusted to Patient's CYP3A Status and NAT2 Genotype

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