Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006605)
Formula
CYP1A2 ...
SVG example
Reactant Dacarbazine Product 5-[3-hydroxymethyl-3-methyl-triazen-1-yl]-imidazole-4-carboxamide (HMMTIC)
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Cytochrome P450 1A1 (CYP1A1) DME Info
Cytochrome P450 2E1 (CYP2E1) DME Info
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006606 5-[3-hydroxymethyl-3-methyl-triazen-1-yl]-imidazole-4-carboxamide (HMMTIC) (5-[3-methyl-triazen-1-yl]-imidazole-4-carboxamide (MTIC) Unclear Dacarbazine [1]
References
1 Pharmacokinetics of dacarbazine (DTIC) in pregnancy

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