Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006664)
Formula
SVG example
N-demethylation
Reactant Hydroxydesmethyl doxepin Product Didesmethyl doxepin
Reactant Info Product Info
Metabolic Type Oxidation - N-demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006662 N-desmethyldoxepin Hydroxydesmethyl doxepin Oxidation - Hydrolyzationn Doxepin hydrochloride [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006663 Hydroxydesmethyl doxepin Hydroxydesmethyl doxepin glucuronide Conjugation - Glucuronidation Doxepin hydrochloride [1]
References
1 Pharmacogenomics knowledge for personalized medicine Clin Pharmacol Ther. 2012 Oct;92(4):414-7. doi: 10.1038/clpt.2012.96.

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