Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006735)
Formula
DCK
SVG example
Reactant Fludarabine phosphate Product 5'-triphosphate (F-ara-ATP)
Reactant Info Product Info
Metabolic Enzyme Deoxycytidine kinase (DCK) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR014192 Fludarabine phosphate Fludarabine Other reaction - Dephosphorylation Fludarabine phosphate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011019 9-beta-D-arabinofuranosyl-2-fluoroadeninete Fludarabine triphosphate Unclear - Unclear Fludarabine [2]
References
1 Prodrugs: design and clinical applications
2 Association of fludarabine pharmacokinetic/dynamic biomarkers with donor chimerism in nonmyeloablative HCT recipients

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