Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006826)
Formula
CYP3A4 ...
SVG example
Hydrolyzationn
Reactant Solifenacin succinate Product 4R-hydroxy solifenacin
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 1A1 (CYP1A1) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006827 Solifenacin succinate 4R-hydroxy-N-oxide solifenacin Unclear Solifenacin succinate [1]
MR006829 Solifenacin succinate N-glucuronide Solifenacin Conjugation - Glucuronidation Solifenacin succinate [1]
MR006828 Solifenacin succinate N-oxide Solifenacin Unclear Solifenacin succinate [1]
References
1 Clinical pharmacokinetics and pharmacodynamics of solifenacin. Clin Pharmacokinet. 2009;48(5):281-302.

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