Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006862)
Formula
UGT1A3 ...
SVG example
O-glucuronidation
Reactant Empagliflozin Product Empagliflozin-2-glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A3 (UGT1A3) DME Info
UDP-glucuronosyltransferase 1A8 (UGT1A8) DME Info
UDP-glucuronosyltransferase 1A9 (UGT1A9) DME Info
UDP-glucuronosyltransferase 2B7 (UGT2B7) DME Info
Metabolic Type Conjugation - O-glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006863 Empagliflozin Empagliflozin-3-glucuronide Unclear Empagliflozin [1]
MR006864 Empagliflozin Empagliflozin-6-glucuronide Unclear Empagliflozin [1]
References
1 Pharmacokinetics, Pharmacodynamics and Clinical Use of SGLT2 Inhibitors in Patients with Type 2 Diabetes Mellitus and Chronic Kidney Disease

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