Details of the Metabolic Reaction (MR)
| General Information of This Metabolic Reaction (MR) (ID: MR006869) | ||||||
|---|---|---|---|---|---|---|
| Formula | Reactant | Encorafenib | Product | Encorafenib dealkylation | ||
| Reactant Info | Product Info | |||||
| Metabolic Enzyme | Cytochrome P450 3A4 (CYP3A4) | DME Info | ||||
| Mephenytoin 4-hydroxylase (CYP2C19) | DME Info | |||||
| Cytochrome P450 2D6 (CYP2D6) | DME Info | |||||
| Metabolic Type | Oxidation - N-dealkylation | |||||
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