Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR006897)
Formula	C-hydroxylation
	Reactant	Loperamide hydrochloride		Product	Loperamide carbinolamide metabolite
	Reactant	Reactant Info		Product	Product Info
Metabolic Type	Oxidation - C-hydroxylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR006896	Loperamide hydrochloride	Loperamide oxide	Oxidation - N-hydroxylation	Loperamide hydrochloride	[1]
MR006895	Loperamide hydrochloride	N-demethyl loperamide	Oxidation - N-demethylation	Loperamide hydrochloride	[1]

References
1	Identification of cytochrome P450 isoforms involved in the metabolism of loperamide in human liver microsomes. Eur J Clin Pharmacol. 2004 Oct;60(8):575-81.

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