Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006939)
Formula
SVG example
Glycosylation
Reactant Aprocitentan Product Macitentan metabolite M1
Reactant Info Product Info
Metabolic Type Conjugation - Glycosylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006938 Aprocitentan Macitentan metabolite M2 Multi-steps Reaction - Hydrolysis; hydroxylation Macitentan [1]
MR006940 Aprocitentan Macitentan metabolite M3 Hydrolysis - Hydrolysis Macitentan [1]
References
1 Clinical pharmacokinetics and pharmacodynamics of the endothelin receptor antagonist macitentan

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