Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007128)
Formula	Demethylation
	Reactant	Encainide	Product	N-desmethylencainide
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Oxidation - Demethylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR007125	Encainide	O-desmethylencainide	Oxidation - Demethylation	Encainide	[1], [2]

Other MR(s) Related to The Product of This MR

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR007129	N-desmethylencainide	N,O-didesmethylencainide	Oxidation - Demethylation	Encainide	[1]

References
1	Oxidative metabolism of encainide: polymorphism, pharmacokinetics and clinical considerations
2	Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I. Clin Pharmacokinet. 2009;48(11):689-723.

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