Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007161)
Formula Reactant Etizolam Product 8-hydroxy-etizolam
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007159 Etizolam alpha-hydroxyetizolam Oxidation - 1'-hydroxylation Etizolam [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007162 8-hydroxy-etizolam Unclear Conjugation - Conjugation Etizolam [3]
References
1 Effects of genetic polymorphism of cytochrome P450 enzymes on the pharmacokinetics of benzodiazepines. J Clin Pharm Ther. 2007 Aug;32(4):333-41.
2 Inhibition of the metabolism of etizolam by itraconazole in humans: evidence for the involvement of CYP3A4 in etizolam metabolism. Eur J Clin Pharmacol. 2004 Aug;60(6):427-30.
3 erowid:Etizolam

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