Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007349)
Formula
SVG example
N-dealkylation
Reactant BRN-0456976 M2 Product BRN-0456976 M1
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A5 (CYP3A5) DME Info
Metabolic Type Oxidation - N-dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007348 BRN-0456976 BRN-0456976 M2 Oxidation - N-dealkylation BRN-0456976 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007350 BRN-0456976 M1 BRN-0456976 M3 Oxidation - Monohydroxylation BRN-0456976 [1]
References
1 Metabolism of carfentanil, an ultra-potent opioid, in human liver microsomes and human hepatocytes by high-resolution mass spectrometry. AAPS J. 2016 Nov;18(6):1489-1499.

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