Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007495)
Formula Reactant Arachidonic acid Product AA-CoA
Reactant Info Product Info
Metabolic Enzyme Thiopurine methyltransferase (TPMT) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007494 Arachidonic acid 19-HETE Other reaction - Omega-hydroxylation Arachidonic acid [1]
MR007493 Arachidonic acid 20-HETE Other reaction - Omega-hydroxylation Arachidonic acid [1]
MR007489 Arachidonic acid EET Unclear Arachidonic acid [1]
MR007492 Arachidonic acid Leukotriens Unclear Arachidonic acid [1]
MR007491 Arachidonic acid Prostaglandin H2 Unclear Arachidonic acid [2], [1]
MR007208 Arachidonic Acid Thromboxanes Oxidation - Cyclooxygenation Gamma-linolenic acid [3]
References
1 Role of cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids. Biochim Biophys Acta. 2011 Jan;1814(1):210-22.
2 Identification and functional characterization of polymorphisms in human cyclooxygenase-1 (PTGS1). Pharmacogenet Genomics. 2007 Feb;17(2):145-60.
3 Gamma-linolenic acid, Dihommo-gamma linolenic, Eicosanoids and Inflammatory Processes

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