Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007646)
Formula
SVG example
Oxidationn
Reactant NSC-149027 Product NSC-149027 M4
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007647 NSC-149027 M4 Bropirimiedihydrodiol(M1) Oxidation - Hydrolyzationn NSC-149027 [1]
MR007648 NSC-149027 M4 m-hydroxybropirimine(M3) Oxidation - Hydrolyzationn NSC-149027 [1]
MR007649 NSC-149027 M4 p-hydroxyborpirimine(M2) Oxidation - Hydrolyzationn NSC-149027 [1]
References
1 Human biotransformation of bropirimine. Characterization of the major bropirimine oxidative metabolites formed in vitro. Drug Metab Dispos. 1998 Oct;26(10):1048-51.

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