Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007670)
Formula
ES
SVG example
Deacetylation
Reactant Nitazoxanide Product Nitazoxanide metabolite T
Reactant Info Product Info
Metabolic Enzyme Esterases (ES) DME Info
Metabolic Type Oxidation - Deacetylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007676 Nitazoxanide Desacetyl-nitazoxanide Oxidation - 3-hydroxylation Nitazoxanide [1]
MR007677 Nitazoxanide Tizoxanide glucuronide Unclear - Unclear Nitazoxanide [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007674 Nitazoxanide metabolite T Nitazoxanide metabolite M2 Unclear - Unclear Nitazoxanide [2]
MR007672 Nitazoxanide metabolite T Nitazoxanide metabolite M3 Conjugation - Glucuronidation Nitazoxanide [2]
MR007675 Nitazoxanide metabolite T Nitazoxanide metabolite M4 Conjugation - Glucuronide conjugation Nitazoxanide [2]
MR007671 Nitazoxanide metabolite T Nitazoxanide metabolite M5 Conjugation - Sulfate conjugation Nitazoxanide [2]
MR007673 Nitazoxanide metabolite T Nitazoxanide metabolite M6 Conjugation - Sulfate congation Nitazoxanide [2]
References
1 DrugBank(Pharmacology-Metabolism):Nitazoxanide
2 Metabolism of nitazoxanide in rats, pigs, and chickens: Application of liquid chromatography coupled to hybrid linear ion trap/Orbitrap mass spectrometer

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