Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007858)
Formula Reactant Pimavanserin Product Pimavanserin metabolite M15
Reactant Info Product Info
Metabolic Type Oxidation - Dihydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007875 Pimavanserin Pimavanserin metabolite M1 Oxidation - Dehydrogenation Pimavanserin [1]
MR007856 Pimavanserin Pimavanserin metabolite M16 Oxidation - Dihydroxylation Pimavanserin [1]
MR007873 Pimavanserin Pimavanserin metabolite M21 Oxidation - Trihydroxylation Pimavanserin [1]
MR007874 Pimavanserin Pimavanserin metabolite M22 Unclear - Unclear Pimavanserin [1]
MR007871 Pimavanserin Pimavanserin metabolite M3 Oxidation - Demethylation Pimavanserin [1]
MR007869 Pimavanserin Pimavanserin metabolite M6 Oxidation - Debutylation Pimavanserin [1]
MR007865 Pimavanserin Pimavanserin metabolite M8 Oxidation - Hydroxylation Pimavanserin [1]
MR007862 Pimavanserin Pimavanserin metabolite M9 Oxidation - Hydroxylation Pimavanserin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007861 Pimavanserin metabolite M15 Pimavanserin metabolite M17 Multi-steps Reaction - Dihydroxylation; dehydrogenated Pimavanserin [1]
MR007860 Pimavanserin metabolite M15 Pimavanserin metabolite M19 Multi-steps Reaction - Dihydroxylation; demethylation Pimavanserin [1]
MR007859 Pimavanserin metabolite M15 Pimavanserin metabolite M20 Multi-steps Reaction - Dihydroxylation; deethylation Pimavanserin [1]
References
1 Investigation of metabolic profile of pimavanserin in rats by ultrahigh-performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry

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