Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008087)
Formula
LE
SVG example
Hydrolysis
Reactant Hetacillin Product Ampicillin
Reactant Info Product Info
Metabolic Enzyme Liver esterases (LE) DME Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008088 Hetacillin Acetone Hydrolysis - Hydrolysis Hetacillin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008908 Bacampicillin Ampicillin Hydrolysis - Hydrolysis Bacampicillin [2]
MR008089 Pivampicillin Ampicillin Hydrolysis - Hydrolysis Pivampicillin [3]
References
1 Biotransformation of hetacillin to ampicillin in man
2 Comparative study of bacampicillin and ampicillin in the treatment of uncomplicated gonorrhoea
3 Absorption of ester prodrugs in Caco-2 and rat intestine models

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