Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008287)
Formula
SVG example
Hydrolysis
Reactant DIADENOSINE TETRAPHOSPHATE Product ADP
Reactant Info Product Info
Metabolic Enzyme diadenosine tetraphosphate (Ap4A) DME Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011011 Adenosine triphosphate Adenosine diphosphate Unclear - Unclear Adenosine triphosphate [1]
MR000070 AMP ADP Other reaction - Phosphorylation Adenosine [2], [3]
MR000075 ATP ADP Other reaction - Dephosphorylation Adenosine [2], [3]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011012 Adenosine diphosphate Adenosine Phosphate Unclear - Unclear Adenosine triphosphate [1]
MR000073 ADP ATP Other reaction - Phosphorylation Adenosine [2], [3]
MR000072 ADP AMP Other reaction - Dephosphorylation Adenosine [2], [3]
References
1 ATP and its metabolite adenosine cooperatively upregulate the antigen-presenting molecules on dendritic cells leading to IFN- production by T cells
2 Adenosine Metabolism: Emerging Concepts for Cancer Therapy Cancer Cell. 2019 Dec 9;36(6):582-596. doi: 10.1016/j.ccell.2019.10.007.
3 Purine signaling pathway dysfunction in autism spectrum disorders: Evidence from multiple omics data. Front Mol Neurosci. 2023 Feb 3;16:1089871. doi: 10.3389/fnmol.2023.1089871.

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